Abstract: In order to select the best optimum excipients for the preparation of Chinese cabbage freezedried powder effervescent tablets and carry out quality inspection, the disintegrating agent (including acid source and alkali source), lubricant, sweetener and adhesive of effervescent tablets were selected and optimized by single factor test and direct compression method. The results showed that the optimal ratio of the ingredients was 28% tartaric acid, 22% sodium bicarbonate, 5% polyethylene glycol 6000, 0.9% aspartame and proper amount of 10% starch, respectively. The effervescent tablet of Chinese cabbage freezedried powder prepared by the above formula had the advantages of simple technology, clear solution, no visible insoluble matter, comfortable taste and certain promotion value. |